Preheat the air-fryer to 400 F. Separate the biscuit dough and cut in half. Roll into balls and place into a greased air-fryer basket.
Air-fry for 8-10 minutes. Place melted butter into a shallow dish. In another shallow dish, combine granulated sugar and pumpkin pie spice. Roll the donut holes in the melted butter, then roll in pumpkin spice mixture.