Cut chicken into 1-inch pieces. Heat oil in a large saucepan to 375 F.
In a shallow dish, whisk together eggs, milk and hot sauce. In another shallow dish, whisk together flour, salt, pepper, paprika, onion powder and garlic powder.
Dip chicken first in milk mixture, then fully coat chicken in flour mixture. Repeat with the remaining chicken. Fry chicken in batches until golden browned. Drain on a wire rack over paper towels.